To showcase the state-of-the-art in the area of clinical male infertility, the January 2012 Special Issue on Clinical Male Infertility contains articles by leading experts on the evaluation of infertile men and a background on the pathophysiology of the diverse causations ofmale infertility. Further background information on this important topic is available through the accompanying web focus which links to related articles from across Nature Publishing Group.

http://www.nature.com/aja/journal/v14/n1/index.html